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Treatment of toxoplasmosis

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Treatment is required in circumstances of severe infection, for example, after clinical symptoms for more than 6 weeks, or superimposed upon HIV infection.

Administer:

  • pyrimethamine - 25-50 mg / 8 h PO for 5 days; then
  • pyrimethamine - 25-50mg / 24h PO for 4 weeks, plus sulphadiazine - 4-6 g / 24h PO

Leucopaenia and thrombocytopaenia may occur with pyrimethamine; give folinic acid, 15 mg daily.

Spiramycin is an alternative to pyrimethamine, but is unsuitable for treating ocular toxoplasmosis. It can cause abdominal pain, nausea and vomiting.

The treatment of toxoplasmosis in specific clinical settings is given in the submenu.


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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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