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Additional investigations

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Specific blood tests and microbiology may be required for certain indications and these are listed below:

  • travel to malarial country - repeated blood films
  • IV drug use or at risk - hepatitis serology (A-E), for HIV or Hepatitis HIV testing
  • thyrotoxicosis - T4, T3, TSH
  • suspected connective tissue disorder - ANF, anti-DNA antibody, CRP
  • specific agent suspected - serial titres for EBV, CMV, influenza, Toxoplasma, Lyme disease, chlamydia, salmonella, Borrelia recurrentis, Q fever, leptospirosis

Other procedures however that may also be considered are:

  • abdominal ultrasound:
    • intra-hepatic, subphrenic or paracolic abscesses
  • white cell labelling:
    • this may show a localised abcess, empyema or osteomyelitis
  • bone scan:
    • this again may identify osteomyelitis or metastatic bone disease
  • CT and MRI:
    • lymphoma or covert tumours
  • echocardiography:
    • infective endocarditis
  • bone marrow:
    • leukaemia or culture for miliary TB
  • biopsy:
    • either endoscopically or percutaneously of suspected area
  • repeat history, examination and certain investigations:
    • if origin of fever remains unknown

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