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Intervention studies

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

There are few intervention studies into the consequences of H. pylori eradication on the incidence of gastric carcinoma.

A Japanese study of 132 H. pylori positive patients undergoing endoscopic resection of early gastric cancer compared the rates of recurrent gastric cancer in patients with or without H. pylori eradication:

  • 9% without eradication had recurrent cancer
  • 0% with eradication had recurrent cancer (p=0.01)

Reference:

  • Uemura, N, Mukai, T, Okamoto, S, et al. (1997). Effect of Helicobacter pylori eradication on subsequent development of cancer after endoscopic reseftion of early gastric cancer. Cancer Epidemiol Biomarkers Prev, 6, 639-42

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