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Ciprofloxacin

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Activity:

Gram negative and Gram positive infections including shigella, salmonella, campylobacter, neisseria, pseudomonas and some mycobacteria. It has only moderate activity against Gram positive bacteria such as Strep influenzae and faecalis. It is active against some mycobacteria and chlamydia. The majority of anaerobic infections are not susceptible to ciprofloxacin

Cautions;

drug interactions
- theophylline levels increase with concurrent ciprofloxacin
- warfarin and other anticoagulants:
  - bleeding time increases
  - monitor creatinine with cyclosporin
epilepsy and history of CNS disorders
patients with AIDS - anaphylaxis has been reported
alkalinity of urine
inadequate fluid intake
renal impairment
Pregnancy and breast feeding
G6PD deficiency
children and growing adolescents - ciprofloxacin is contra-indicated except where the benefits of treatment outweigh the risks

Routes of administration:

oral
tablets
i.v. infusion
eye drops

The summary of product characteristics should be consulted before prescribing this drug.

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Ciprofloxacin

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