This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Intensification (consolidation) phase

Authoring team

After restoring normal haematopoiesis, intensification therapy is used to reduce the risk of a relapse by removing the drug-resistant residual leukaemic cells (1).

There is little consensus regarding the best regimens and duration of treatment.

  • the following strategies are used frequently in childhood ALL:
    • high-dose methotrexate plus mercaptopurine,
    • reinduction treatment - use of the same drugs which was given initially
    • high-dose asparaginase for an extended period (2)
  • for adults, a standard intensification regimen is absent but post remission therapy with cytarabine, cyclophosphamide, anthracyclines and methotrexate have been shown to be effective according to several non randomised trials

Reference:

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.