Normal screen
Patients with normochromic normocytic anaemia, a normal/reduced reticulocyte count and normal blood tests may require a bone marrow biopsy.
Althought the diagnostic yield from bone marrow biopsy in this situation is low, the possible outcomes include:
- hypoplastic anaemia
- bone marrow infiltration:
- metastatic cancer
- leukaemia
- myeloma
- myelofibrosis
- sideroblastic anaemia
- myelodysplasia
- masked megaloblastic anaemia
Reference:
- Elis, A. et al. (1996). A clinical approach to idiopathic normocytic-normochromic anemia. J Am Geri Soc 44(7), 832-4
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