Nitrofurantoin induced agranulocytosis
Idiosyncratic drug-induced agranulocytosis is a rare life-threatening adverse reaction characterised by an absolute neutrophil count <500 cells/muL of blood
A review noted (1):
A more recent review notes (2):
According to worldwide adverse drug reaction data, approximately 0.0004% of nitrofurantoin treatments have resulted in hematologic reactions (3).
Reference:
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