This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Diagnosis

Authoring team

The clinical features of aplastic anaemia are non-specific. Diagnosis is based upon:

  • peripheral blood:
    • neutrophils less than 0.5 x 10^9 per litre
    • platelets less than 20 x 10^9 per litre
    • reticulocyte count corrected for haematocrit less than 1%
  • marrow:
    • severe hypocellularity
    • moderate hypocellularity with < 30% of residual cells being haematopoietic

At least two peripheral plus one marrow criteria must be satisfied.

Reference

  1. Kulasekararaj A, Cavenagh J, Dokal I, et al. Guidelines for the diagnosis and management of adult aplastic anaemia: a British Society for Haematology Guideline. Br J Haematol. 2024 Mar;204(3):784-804.

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.