previously HRT was considered a treatment option. However results from the Women's Health Initiative revealed that HRT was associated with increased incidence and severity of urinary incontinence (UI) (1)
the authors concluded that conjugated equine estrogen (CEE) alone and CEE + medroxyprogesterone acetate (MPA) increased the risk of UI among continent women and worsened the characteristics of UI among symptomatic women after 1 year. Conjugated equine estrogen with or without progestin should not be prescribed for the prevention or relief of UI
the WHI study results confirmed earlier findings of the HERS trial (2)
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