This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Chemotherapy treatments

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Chemotherapy may be indicated in:

  • advanced disease - with extrapelvic spread
  • recurrent disease
  • where radiotherapy has been ineffective

Most treatments are based on cytotoxics based on cisplatin.

Chemotherapy is not a first choice treatment because:

  • cervical carcinoma is relatively radiosensitive
  • large, bulky tumours may have necrotic centres which are never reached
  • tissue vascularity is reduced following radiotherapy so drug uptake is sub-optimal

However, objective improvement is reported in 50-65% of cases.

NICE state that (1):

  • topotecan in combination with cisplatin is recommended as a treatment option for women with recurrent or stage IVB cervical cancer only if they have not previously received cisplatin

Reference:

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.