with respect to adults aged 15+ years in England and Wales in 1992 - the total new cases was 5,384 and the number per annum per 2000 population was 0.21 (1)
risk with respect to family members affected by ovarian cancer (2):
woman with a mother with ovarian cancer - relative risk = 6
woman with a sister with ovarian cancer - relative risk = 3.8
woman with a daughter with ovarian cancer - relative risk = 1.1
if a woman has two close relatives with ovarian cancer then her risk of developing ovarian cancer is approximately 40%
the BRCA1 and BRCA2 genes are associated with ovarian, breast and other cancers
women with BRCA1 have a 50% lifetime risk of developing ovarian cancer (3)
women with BRCA2 have a 30% lifetime risk of developing ovarian cancer (3)
Reference:
(1) Referral Guidelines for Suspected Cancer (April 2000). NHS Executive.
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