Diuretics, especially spironolactone (e.g. 25 mg per day from day 18 to 26 of the cycle), may be used to reverse fluid retention and to reduce PMS symptoms such as breast tenderness and mood symptoms (1,2).
Thiazides have not been found to have any effect in the treatment of PMS symptoms (3)
Reference:
Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.