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Most prominent signs according to age of individual with Klinefelter's syndrome

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most prominent signs according to period of life in patients with Klinefelter’s syndrome

Birth

  • cryptorchidism
  • small penis
  • scrotum bifidus
  • hypospadia
  • fifth finger clinodactily
  • cleft palate
  • inguinal hernia
  • hypotonia

Infancy

  • small testes
  • small penis size
  • speech and language deficits
  • long legs and arms

Childhood

  • speech and language deficits
  • learning disabilities
  • psychological difficulties
  • behavioral issues

Puberty

  • long legs and arms
  • gynaecomastia
  • sparse facial, body and pubic hair
  • gradual increase of FSH and LH

Adulthood

  • small and firm testes
  • gynaecomastia
  • sparse facial, body and pubic hair
  • infertility
  • sexual dysfunction
  • metabolic syndrome

Reference:

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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