The two most important features in the walls of atherosclerotic aneurysms are:
The adventitia is compressed and is often the site of a lymphocytic infiltrate which may be a response to the presence in the lesion of oxidised lipid or 'ceroid'.
AAA has a familial pattern with a prominent genetic component. For reasons that are unclear, in population based studies, diabetics have a lower incidence of aneurysms than non diabetics (1).
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