Sampling is performed under ultrasound control.
The approach may be transcervical or transabdominal:
The transabdominal route is preferred because the risk of infection is thought to be lower and it can be used throughout the 2nd and 3rd trimesters.
Rhesus negative mothers should receive anti-Rhesus D immunuoglobulin i.m. after the procedure.
showing the transcervical method for chorionic villus sampling:
Showing the transabdominal approach:
Reference:
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