After an incubation period of three to six days, presentation may vary in severity from non-specific, self-limited symptoms of fever, malaise, photophobia and headache to an illness of sudden onset with fever, vomiting and prostration which may progress to jaundice and haemorrhage (1).
The presentation may be divided into two phases:
For local populations in endemic areas, the overall fatality ratio is about 5%, rising to 20–30% once jaundice and severe symptoms occur.
In nonimmune travellers and migrants, and during epidemics in areas that have low levels of yellow fever activity, the case fatality rate can exceed 50%
Reference:
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