This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Treatment of reactions

Authoring team

Type I reactions:

  • salicylates
  • chloroquine
  • non-steroidal anti-inflammatory agents
  • corticosteroids are indicated when there is:
    • severe nerve involvement, or nerve abscess
    • impending paralysis
    • extensive and acutely inflamed skin lesions
  • physiotherapeutic measures, such as rest and splinting

Mild type II reactions:

  • salicylates, chloroquine and non-steroidals are again the mainstay

Moderate/severe type II reactions:

  • thalidomide (300-400mg/day) is the drug of choice
  • clofazimine (200-300mg/day) may be useful but is slow-acting and may have toxic effects with prolonged use
  • corticosteroids are best avoided except in patients with severe neuritis, eye complications or orchitis

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2025 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.