Detection of adverse drug reactions is very difficult. For example, a premarket trial of 3000 patients will, with a poisson distribution, detect 1 adverse effect if there is an incidence of 1 in 1000, assuming no background incidence. The higher the background incidence with a rare adverse effect, the harder the adverse effect is to detect.
Surveillance and detection is by:
Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.