Management
Immunosuppressive therapy should be commenced promptly after transplantation. The most popular regime is to prescribe cyclosporin A alone, or together with prednisolone and/or azathioprine i.e. mono, double or triple therapy.
Graft rejection should be monitored by:
- serum creatinine - a rise in levels during the first days or weeks after transplantation may be due to rejection or to other causes, for example, cyclosporin toxicity
- renal biopsy
Treatment of acute rejection consists of:
- high-dose intravenous steroids
- anti-thymocyte immunoglobulin
Mycophenolate mefetil may have a role in maintenance immunosuppression and in the treatment of acute rejection.
Related pages
Create an account to add page annotations
Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.