Zone of stasis
The zone of stasis is an area surrounding the zone of coagulative necrosis where cellular damage is less severe. This area has a diminished blood supply that may be further compromised by excessive local production of inflammatory mediators. Hence, a burn that initially is assessed as partial thickness may progress to full-thickness with time. Modern burn management aims to push this dynamic process in a more favourable direction by:
- restoring tissue perfusion with adequate volume replacement
- early excision and skin grafting of necrotic skin with reduced production of inflammatory mediators
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