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Zone of stasis

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

The zone of stasis is an area surrounding the zone of coagulative necrosis where cellular damage is less severe. This area has a diminished blood supply that may be further compromised by excessive local production of inflammatory mediators. Hence, a burn that initially is assessed as partial thickness may progress to full-thickness with time. Modern burn management aims to push this dynamic process in a more favourable direction by:

restoring tissue perfusion with adequate volume replacement
early excision and skin grafting of necrotic skin with reduced production of inflammatory mediators

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