Pharmacokinetics of antibiotics

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Features which must be taken into account in the pharmacokinetics of antibiotics include:-

meningitis - penetration of antibiotics into CSF

osteomyelitis - bone penetration, penicillin resistant organisms - linomycin, clindomycin, fusidic acid

bile - ampicillin, amoxycillin, tetracycline

infective endocarditis, high doses - valve tissue, vegetations

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Pharmacokinetics of antibiotics

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