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Yersinia enterocolitica

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Infection with Yersinia enterocolitica results in a number of clinical syndromes which are dependent on the host’s age. Possible clinical presentations include enterocolitis, acute mesenteric lymphadenitis or terminal ileitis.

Enterocolitis - this is characterised by fever, diarrhoea and severe abdominal pain. This condition may be mistaken for acute appendicitis. Serological tests showing a rising titre of Y. enterocolitica antibodies is strongly suggestive of acute yersinosis but this result is generally only available after recovery. This condition is normally self-limiting. Treatment with antibiotics (e.g. tetracycline) is controversial and is based on clinical judgement.

This is infection with a member of the Yersinia species. There are three major human pathogens;

  • Yersinia pestis, which causes plague
  • Yersinia pseudotuberculosis which causes mesenteric lymphadenitis
  • Yersinia enterocolitica which causes enterocolitis

Summary: Yersinia pseudotubercolosis and Yersinia entercolitica


  • Yersinia enterocolitica and Yersinia pseudotuberculosis


  • Asymptomatic carriage in the gastrointestinal tract of wild and domesticated animals and birds, particularly pigs for Y. enterocolitica


  • most commonly seen in those less than 15 years of age
  • seasonal variation occurs - Y. pseudotuberculosis is more common in winter and Y. enterocolitica is more common from June to November


  • Faecal-oral:
    • consumption of contaminated food or water, particularly pork or pork products. A wide variety of foodstuffs have been implicated in cases and outbreaks
  • person-to-person: particularly within nurseries, schools and healthcare settings
  • direct contact with animals
  • Via contaminated blood products

Incubation period:

  • Y. enterocolitica: usually 3-7 days with extremes of 1-12 days reported
  • Y. pseudotuberculosis: range of 2-25 days reported (median 5-8 days)

Common clinical features:

  • Y. enterocolitica:
    - watery diarrhoea, abdominal pain, fever
    - duration: 2 days to 6 weeks
    - complications: reactive arthritis, erythema nodosum, septicaemia
  • Y. pseudotuberculosis:
    - mesenteric adenitis, fever, abdominal pain often mimicking appendicitis
    - duration: 1-37 days (average 18 days)
    - complications: reactive arthritis, erythema nodosum, acute renal failure


  • excretion of the organism in stool may persist for several months after infection but infectivity decreases substantially after the first 4 days or so


  • PHE (2019). Recommendations for the Public Health Management of Gastrointestinal Infections

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