Point of care trypsinogen test for diagnosis of acute pancreatitis

• point-of-care urine trypsinogen test for the diagnosis of pancreatitis in the emergency department (1,2):
  
  
  • sensitivity and specificity of urine trypsinogen for acute pancreatitis was examined in a small study and was, respectively, 100% (95% confidence interval [CI] = 77% to 100%) and 96% (95% CI = 92% to 98%)
    
    
  • the authors concluded that urine trypsinogen screening test for pancreatitis compared favourably with plasma lipase and amylase levels

Reference:

1. Banks PA et al. Classification of acute pancreatitis--2012: revision of the Atlanta classification and definitions by international consensus. Gut. 2013;62(1):1
2. Simha A et al. Utility of point-of-care urine trypsinogen dipstick test for diagnosing acute pancreatitis in an emergency unit. Biomark Med. 2021 Oct;15(14):1271-1276.