Clinical features
The history is important, and should include:
- name of drug taken
- how many
- when
Initial features tend to be non-specific, and usually consist of nausea and vomiting. Patients may be asymptomatic for the first 24 hours after ingestion.
After a period of apparent recovery, there may be tender hepatomegaly and acute hepatic failure with encephalopathy. Hypotension, hypoglycaemia, and acute tubular necrosis may occur.
Reference
- National Poisons Information Service. TOXBASE. Paracetamol. 2023 [internet publication].
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