Alkaline phosphatase (raised, related to medication)
There are many drugs (1,2) that may result in a raised alkaline phosphatase. It is important to consider that a medication may be the cause of an isolated raised alkaline phosphatase - but also consider other possible causes as well.
Some examples of drugs that may cause a raised alkaline phosphatase include:
- Antibiotics:
- penicillin derivatives (1)
- nitrofurantoin
- erythromycin
- aminoglycosides (1)
- sulfonamides (2)
- trimethoprim-sulfamethoxazole (2)
- Antiepileptic drugs:
- Carbamazepine
- Phenobarbital
- Phenytoin
- Valproic Acid
- Antihistamines:
- Cetirizine (1)
- Cetirizine (1)
- Cardiovascular drugs:
- Captopril (1)
- Diltiazem
- Felodipine (1)
- Verapamil (2)
- Quinidine (2)
- Flutamide (2)
- Disease modifying agents:
- Penicillamine
- Sulfa drugs (1)
- Gold salts (2)
- Polycyclic aromatic hydrocarbons:
- Oestrogens
- Anabolic Steroids (2)
- Steroids (1)
- Methyltestosterone (2)
- Psychotropic drugs:
- Monoamine oxidase inhibitors
- Phenothiazines e.g. chlorpromazine (1,2)
- Diabetes drugs:
- tolbutamide
- chlorpropamide
- tolazamide
- Other drugs:
- Allopurinol
- Methimazole
- Disulfiram
- Phenylbutazone
Reference:
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