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Aetiology with respect to mechanism

Authoring team

  • raised intra-abdominal pressure, e.g. obesity, eating large meals, tight clothing, pregnancy
  • faulty oesophageal sphincter, e.g. pregnancy - due to hormonal smooth muscle relaxation, smoking, fatty meals, hiatus hernia, after surgery for achalasia
  • drugs, e.g. tricyclic depressants, anticholinergics which affect the function of the lower oesophageal sphincter

Acidic damage to the lower oesophageal mucosa can cause reflex longitudinal muscle spasm. This draws the cardia upwards, so further permitting acid reflux.

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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