A Warthin's tumour is a benign tumour that occurs almost exclusively in the parotid glands, primarily in the tail. It accounts for about 5% of all parotid tumours. 10% occur bilaterally. It usually arises after middle age, with a male:female ratio of 5:1. There is a strong association with smoking.
It is composed of large glandular acini, embedded in dense lymphoid tissue in which lymphoid follicles may be seen. It is thought to arise from the salivary duct epithelium, the lymphoid tissue originating from the lymphoid aggregates present in the normal parotid gland.
The tumour presents as a soft, cystic lump. It alone, among salivary neoplasms, will concentrate technetium 99m. Warthin tumours are said to exude a highly-characteristic yellow or brown fluid if damaged.
Treatment is by superficial parotidectomy. Recurrence is rare but a satellite lesion may enlarge and present as another tumour. Prognosis after operation is good.
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