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Mechanisms of nasal obstruction

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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The prime control of nasal resistance and therefore, of physiologic nasal obstruction, is the state of congestion of blood vessels in the inferior turbinates and the anterior nasal septum. Parasympathetic vasodilatation causes engorgement of blood vessels; sympathetic vasoconstriction relieves it.

Factors that increase the sensation of obstruction involve reduced sympathetic, or increased parasympathetic tone, for example:

  • infective, allergic and vasomotor rhinitis
  • hyperventilation - by causing a decrease in pCO2
  • alcohol - by causing peripheral vasodilatation
  • supine posture
  • aspirin
  • cold air
  • sympathetic antagonists e.g. reserpine

Factors that alleviate blockage increase sympathetic, or reduce parasympathetic tone. These include:

  • exercise - acts systemically and therefore, better than topical decongestants
  • sympathomimetrics e.g. ephedrine
  • atrophic rhinitis
  • erect posture
  • rebreathing - by causing an increase in pCO2
  • prostanglandin E2

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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