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Management of copper deficiency

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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management

Treatment of hypocupraemia includes management of the underlying cause and prompt reversal of the deficiency with intravenous copper infusion, oral supplementation of copper, or both

  • copper gluconate, copper sulphate, and copper chloride salts are used commonly

The American Society for Metabolic and Bariatric Surgery Clinical Practice guidelines recommendations:

  • routine oral copper supplementation (2 mg/d)
  • for severe deficiency - IV copper (2-4 mg/d) for six days
  • subsequent treatment, or treatment of mild to moderate deficiency - oral copper (3-8 mg/d) until levels normalise

With treatment, haematological abnormalities return to normal values within 4 to 12 weeks.

Adequacy of replacement should be monitored by periodic assessment of serum copper (1)

Reference:

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