This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Contraindications to testosterone therapy

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Contraindications to testosterone therapy

The main contraindications to testosterone therapy (T therapy) are:1

  • Prostate cancer (locally advanced or metastatic)
  • Male breast cancer
  • An active desire to father children
  • Haematocrit >54%
  • Severe chronic heart failure (NYHA class IV)

An unevaluated prostate nodule or induration, or raised prostate specific antigen (PSA), should be fully investigated prior to starting T therapy.

Untreated sleep apnoea and severe LUTS have previously been considered contraindications to T Therapy, but more recent evidence suggests this may no longer be the case.2 These conditions should however, be fully investigated and optimally manged before starting treatment with testosterone.


Create an account to add page annotations

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.