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Differential diagnosis

Authoring team

The differential diagnosis of hyperthyroidism includes: (1)

  • weight loss despite eating - diabetes, malabsorption
  • anxiety states:
  • differentiation may be difficult clinically
  • positive findings for thyrotoxicosis are eye signs, proximal myopathy, wasting, hyperdynamic circulation with warm peripheries
  • anxiety tends to cause clammy hands
  • phaeochromocytoma:
    • especially if the patient is hypertensive (2)

Reference:

  1. Thyroid disease: assessment and management. NICE guideline NG145. Published: 20 November 2019 Last updated: 12 October 2023
  2. Devereaux D, Tewelde SZ. Hyperthyroidism and thyrotoxicosis. Emerg Med Clin North Am. 2014;32(2):277-92

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