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Bone biopsy for the diagnosis of osteoporosis

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A transiliac biopsy may be used if the diagnosis of osteoporosis is in doubt, to exclude other bone disease and confirm the presence of osteoporosis. The usual findings are:

  • reduced trabecular bone volume, often with low or normal bone turnover
  • a few sites of active bone resorption or formation
  • no osteoid accumulation
  • no marrow fibrosis or plasma cell nests

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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