Features due to local effects
Where hypopituitarism has a neoplastic or infiltrative aetiology the following clinical features may be present:
- headache
- visual field defects:
- most commonly a superior bi-temporal quadrantanopia
- progressing to a bitemporal hemianopia
- cerebrospinal fluid rhinorrhoea due to inferior extension of the tumour
- III, IV and VI nerve palsies due to lateral extension of the tumour
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