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Investigations

Authoring team

The investigation of a suspected case of pyoderma gangrenosum should include:

  • skin biopsy:
    • for culture to detect bacteria and fungi
    • for histology to detect malignancy and vasculitis

  • gastrointestinal imaging in selected patients:
    • barium meal and enema

  • blood tests to detect:
    • paraproteinaemia
    • antiphospholipid antibody
    • antinuclear antibody
    • ANCA

  • full blood count and blood smear
  • bone marrow examination in selected patients

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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