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Laboratory events in monitoring penicillamine

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Event:

Value

Action

leucopaenia

<3.5 x 10^9/l

stop and seek advice

neutropaenia

<2.5 x 10^9/l

stop and seek advice

thrombocytopaenia

<150 x 10^9/l

stop and seek advice

sequential falls in WCCs or PMNs

>10% on 3 occasions

stop and seek advice

sequential falls in platelets

>10% on 3 occasions

stop unless falls are from a high level, which is a response to treatment

haematuria

trace or +

continue drug

haematuria

++ or +++

stop drug, check MSU, consider other causes, seek advice

proteinuria

trace or +

continue drug

proteinuria

++ or +++

stop drug, check MSU, 24-hour urinary proteint, seek advice

Also check local prescribing guidance.

 

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