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Fong Disease

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Nail-patella syndrome also known as Iliac Horn syndrome, Hereditary Onychoostedysplasia, Fong Disease or Turner-Kiser syndrome is a congenital nail disorder with an autosomal dominant inheritance (1).

The disease is characterized by

  • nail and elbow dysplasia
  • patellar aplasia or hypoplasia
  • iliac horns (1).

Other involved sites include

  • kidneys
  • eyes - open-angle glaucoma, cloverleaf dark pigmentation of the iris, micro and sclerocornea, and cataracts
  • central and/or peripheral nervous systems - peripheral polyneuropathy and vasomotor dysfunction (uncommon) (1)



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