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Clinical features

Authoring team

These include:

  • brown follicular keratotic papules distributed over the seborrheic areas of the body - chest, back, ears, nasolabial folds, scalp and groin
  • flat wartlike papules on the dorsa of the feet and hands
  • punctate keratoses on the palms and soles - raised or with a central pit
  • nails show longitudinal pink or white bands with characteristic V-shaped notches at the free edges of the nail plates
  • white centrally depressed papules of the mucosae of the cheeks, hard and soft papules, and gums
  • exceptionally, permanent alopecia

Systemically, there may be:

  • diminished intelligence
  • chronic herpetic and bacterial infections secondary to a defect in delayed hypersensitivity

References:

  1. Khachemoune A, Lockshin B.N. Chronic papules on the back and extremities. JFP 2004;53(5).
  2. Szigeti R, Kellermayer R. Autosomal-Dominant Calcium ATPase Disorders. JID 2006;126:2370-2.

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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