Clinical features
These include:
- brown follicular keratotic papules distributed over the seborrheic areas of the body - chest, back, ears, nasolabial folds, scalp and groin
- flat wartlike papules on the dorsa of the feet and hands
- punctate keratoses on the palms and soles - raised or with a central pit
- nails show longitudinal pink or white bands with characteristic V-shaped notches at the free edges of the nail plates
- white centrally depressed papules of the mucosae of the cheeks, hard and soft papules, and gums
- exceptionally, permanent alopecia
Systemically, there may be:
- diminished intelligence
- chronic herpetic and bacterial infections secondary to a defect in delayed hypersensitivity
References:
Related pages
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