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Side effects

Authoring team

The side-effects of amiodarone are time and dose related.

Minor side effects of amiodarone include corneal microdeposits.

Moderate side effects include:

  • photosensitivity
  • skin discolouration
  • abnormal thyroid function, and abnormal TFTs
  • nausea
  • nightmares
  • sleep disturbance

Serious side effects include:

  • peripheral neuropathy

  • disturbed hepatic function:
    • acute hepatitis and jaundice are particularly associated with intravenous administration
    • chronic toxicity may cause fibrosis or cirrhosis

  • amiodarone lung

  • amiodarone has some proarrhythmic potential

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