Side effects
The side-effects of amiodarone are time and dose related.
Minor side effects of amiodarone include corneal microdeposits.
Moderate side effects include:
- photosensitivity
- skin discolouration
- abnormal thyroid function, and abnormal TFTs
- nausea
- nightmares
- sleep disturbance
Serious side effects include:
- peripheral neuropathy
- disturbed hepatic function:
- acute hepatitis and jaundice are particularly associated with intravenous administration
- chronic toxicity may cause fibrosis or cirrhosis
- amiodarone lung
- amiodarone has some proarrhythmic potential
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