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Weight loss associated with HIV infection

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10-15% of patients suffering from AIDS lose more than 10% of their body weight in the absence of other detectable underlying disease.

Wasting may be due to a number of factors including anorexia, malabsorption and occult infection. These are contributed to by infective damage to the jejunum, and a cytokine mediated increase in metabolic rate.

In a child there may be failure to thrive.

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