Diagnosis
If the diagnosis of thiamine deficiency is in doubt, then treat. There should be a high index of suspicion in areas of endemic thiamine deficiency.
In cases of suspected wet beri-beri, a rapid improvement in the cardiac function following thiamine administration is diagnostic.
Blood biochemistry is deranged in thiamine deficiency states:
- lactate and pyruvate concentrations are raised
- transketolase activity of erythrocytes is low in the absence of added thiamine pyrophosphate but increases by more than 30% upon addition of thiamine pyrophosphate to the patient
- reduced urinary thiamine excretion
Create an account to add page annotations
Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.