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Radiological appearance of hyaline membrane disease

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Aspirated surfactant can be used as a diagnostic tool. If the ratio of phospholipids, lecithin to sphingomyelin, is reduced within the surfactant e.g. less than 2, there is an increased likelihood of respiratory distress syndrome.

Radiography of the chest has two characteristic features:

  • widespread minute reticulogranular densities - ground glass appearance
  • air bronchogram

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