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Clinical features of primum defect

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The clinical features include:

  • heart failure: this in infancy or childhood
  • pulmonary hypertension: especially in Downs syndrome - pulmonary ejection systolic murmur and mid-diastolic tricuspid murmur reflecting increased flow
  • cardiac enlargement
  • breathlessness at rest
  • Harrison's sulci – indentation on the chest along the 6th rib, which is usually bilateral but can also occur unilaterally
  • pink with normal pulses
  • apical pansystolic murmur: if the mitral valve is incompetent

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