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The uptake of radioiodine (I,125) labelled fibrinogen may be used to detect thrombus throughout the calf and in the lower three quarters of the thigh.
It is a highly sensitive technique. Only 50% of DVT's detected on labelled fibrinogen scanning are identified clinically and studies using this technique reveal post operative DVT in up to 30% of patients over 40 years old.
Despite these results, however, the technique is falling out of favour, as: