Homeostatic model assessment for insulin resistance (HOMA - IR)

Homeostatic model assessment for insulin resistance (HOMA - IR)

• based on fasting glucose and insulin measurements;
• derived from the product of the insulin and glucose values divided by a constant, that is, calculated by using the following formula:
  
  
  • fasting glucose (mg/dL) X fasting insulin (mU/L) / 405 (for SI units: fasting glucose (mmol/L) X fasting insulin (mU/L) / 22.5)
    
    
  • a value greater than 2 indicates insulin resistance

Reference:

• 1) Mari A, Ahrén B, Pacini G. Assessment of insulin secretion in relation to insulin resistance. Curr Opin Clin Nutr Metab Care. Sep 2005;8(5):529-33.