FH (familial hypercholesterolaemia) - when to screen a child for FH

• FH Testing in children:
  • in children aged 0-10 years at risk of FH because of 1 affected parent, offer a DNA test at the earliest opportunity. If testing of a child at risk has not been undertaken by the age of 10 years, offer an additional opportunity for a DNA test
    
    
  • in children at risk of homozygous FH because of two affected parents or because of the presence of clinical signs, for example, cutaneous lipid deposits (xanthomata), LDL-C concentration should be measured before the age of 5 years or at the earliest opportunity thereafter. If the LDL-C concentration is greater than 11 mmol/l then a clinical diagnosis of homozygous FH should be considered

Reference:

• (1) NICE (November 2017). Identification and management of familial hypercholesterolaemia