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CK in skeletal muscle disease

Authoring team

CK is raised in:

  • muscular dystrophies - very high early in the early stages of Duchenne muscular dystrophy; levels decrease with time. There is an increased proportion of CK-MB.
  • polymyositis
  • rhabdomyolysis
  • elevated levels are found in up to 40% of patients with motor neurone disease and in some other conditions associated with denervation

Note that strenuous exercise increases levels.

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