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Differential diagnosis

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The diagnosis of angina usually assumes that the cause is atherosclerosis. Other causes of cardiogenic chest pain include: (1)

  • aortic stenosis
  • hypertrophic cardiomyopathy
  • mitral valves prolapse (Barlow's syndrome)
  • aortic dissection
  • pulmonary embolism
  • coronary artery spasm

Pain similar to angina may be caused by:

  • gastrointestinal disease:
    • gastro-oesophageal acid reflux
    • oesophagitis
    • biliary colic
    • gastritis
    • pancreatitis
  • musculoskeletal pain:
    • Bornholm's syndrome
    • Tietze's syndrome
  • psychiatric
    • anxiety disorders - hyperventilation, panic disorder o affective disorder - depression

Reference:

1. Gulati M, Levy PD, Mukherjee D, et al. 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the evaluation and diagnosis of chest pain: A report of the American College of Cardiology/American Heart Association joint committee on clinical practice guidelines. Circulation. 28 Oct 2021

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