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Adrenaline in children with anaphylaxis

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

For teachers or parents giving adrenaline in the community the dosage has to be very clear, and the route is usually intramuscular. In this instance the dose is:

Doses of emergency drugs for anaphylaxis and angio-oedema (1,2):

Drugs

Adult or child older than 12 years

Child aged 6-12 years

Child aged 6 months - 6 years

Child aged under 6 months

Adrenaline (IM*) 1:1000 (repeat after 5 minutes if no better)

500 micrograms (0.5 mL)

(give 300 micrograms IM [0.3 mL] in a child who is small or prepubertal)

300 micrograms (0.3 mL)

150 micrograms (0.15 mL)

100-150 micrograms (0.1 to 0.15 mL)

* IM: intramuscular

Notes:

  • the majority of anaphylaxis episodes occurring in a community setting will respond to initial treatment with IM adrenaline, although currently around 10% receive more than one dose (2)
    • this may sometimes be due to the use of auto-injectors which cannot deliver an age/weight-appropriate dose in most patients
    • less than 1% of reactions are refractory to initial adrenaline treatment, and intensive care admissions for anaphylaxis are uncommon

Reference:

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