This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Adrenaline in adults with anaphylaxis

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Doses of emergency drugs for anaphylaxis and angio-oedema (1,2):

Drugs

Adult or child older than 12 years

Child aged 6-12 years

Child aged 6 months - 6 years

Child aged under 6 months

Adrenaline (IM*) 1:1000 (repeat after 5 minutes if no better)

500 micrograms (0.5 mL)

(give 300 micrograms IM [0.3 mL] in a child who is small or prepubertal)

300 micrograms (0.3 mL)

150 micrograms (0.15 mL)

100-150 micrograms (0.1 to 0.15 mL)

* IM: intramuscular

Notes:

  • the majority of anaphylaxis episodes occurring in a community setting will respond to initial treatment with IM adrenaline, although currently around 10% receive more than one dose (2)
    • this may sometimes be due to the use of auto-injectors which cannot deliver an age/weight-appropriate dose in most patients
    • less than 1% of reactions are refractory to initial adrenaline treatment, and intensive care admissions for anaphylaxis are uncommon

Reference:

Related pages

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.