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DiGeorge syndrome

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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The DiGeorge syndrome is an example of a selective T-cell deficiency caused by the failure of development of the third and fourth pharyngeal pouches.

These pouches give rise to the following structures:

  • thymus
  • parathyroids
  • aortic arch
  • portions of the lips and ears

Consequently, DiGeorge syndrome may present with as immune deficiency state - usually T cells, but sometimes B cells, and also aberrant calcium metabolism, congential heart disease and abnormal facies.


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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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